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5-HTP (5-hydroxytryptophan)

5-HTP (5-hydroxytryptophan) is a natural amino acid precursor to the neurotransmitters serotonin and melatonin. Therefore, it is often taken as a sleep aid at night and a mood regulator for the day, among other uses.

One drawback of an ordinary 5-HTP supplement is its short half-life. (See: PubMed - Kinetics of l-5-hydroxytryptophan in healthy subjects.) The body can break it down and dispose of it more quickly than we might prefer, meaning the supplement wears off quickly. However, there are some sustained release formulas of 5-HTP to ensure a steady supply of serotonin.

Note: 5-HTP is very much not recommended for people currently on any SSRI medication or any medication to treat Parkinson's.

Where to get 5-HTP

  • iHerb - 5-HTP supplements catalog and Natrol 5-HTP Time Release formula
  • Powder City - 5-HTP (Griffonia Seed Extract)

Kratom Alternatives – Herbs, Supplements and More

September 27, 2016 By Pill Scout Leave a Comment

Kratom alternatives are a very hot subject right now. As you may have already learned, the DEA is set to list kratom (mitragyna speciosa) as a Schedule I substance come September 30th 2016. (Update: The DEA have delayed their scheduling pending public commentary.) This is being fought tooth and nail, and quite effectively I might […]

Filed Under: Mood Enhancers Tagged With: 5-HTP, Cannabis, Kava Kava, Kratom, Lemon Balm, Theanine, Tianeptine

Why 5-HTP Doesn’t Work – A review of Natrol’s 5-HTP TR

January 25, 2016 By Pill Scout Leave a Comment

5-HTP is a commonly recommended supplement because it’s natural, the body metabolizes it into the neurotransmitters we want when taking it (serotonin and melatonin), and when taking it in sufficient dosage, (up to 100 mg or so) it can help us get some quality sleep. There is a very important reason to learn why some […]

Filed Under: Mood Enhancers, Nutritional Supplements Tagged With: 5-HTP

How to beat seasonal depression (SAD) symptoms this year

October 7, 2014 By Pill Scout 1 Comment

Fall is here, so is a major change in mood. If you’re like me, you enjoy the crisp, cold air and the crunchy orange leaves that litter the streets. However, it can be hard to shake that sinking feeling that comes with the changes and all the activities that are brought indoors due to the […]

Filed Under: Mood Enhancers, Nutritional Supplements Tagged With: 5-HTP, Caffeine, Fish Oil, Flaxseed, Mucuna Pruriens (Velvet Bean), Omega-3 Fatty Acid, St. John's Wort, Vitamin D, vitamin k2

Stop depressive symptoms with these supplements

September 30, 2013 By Pill Scout 5 Comments

I’ve already written the preface to this article on my alternate blog, linked at the bottom. In short, I explained that “depression” is a cluster of symptoms that academics and mainstream medicine diagnose as a chemical condition. It’s their job to deal with it in terms of pills and brain chemicals. In contrast I acknowledged […]

Filed Under: Mood Enhancers, Nutritional Supplements Tagged With: 5-HTP, ALCAR, Green Tea, Omega-3 Fatty Acid, Vitamin D

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This website and the opinions, content and sources cited within are presented strictly for information purposes only. Many, if not all of the claims within have not been evaluated or advised by the FDA or any other such regulatory body. Any and all professional studies or sources cited take place in controlled settings and may not represent typical results for everyone. Nothing on this site is intended to substitute advice, treatment or diagnosis of a doctor or other health professional.

Always, especially when in doubt, consult with your doctor or health care provider before making any lifestyle changes or taking any supplements or drugs.

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